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Schlafdauer und Übergewicht

Sleep duration and overweight

  • Leitthema
  • Published:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

Zusammenfassung

Schlafmangel ist aufgrund seiner vielfältigen Auswirkungen, deren Wirkmechanismen wir erst zu verstehen beginnen, als ernst zu nehmender Risikofaktor mit großer Public-Health-Relevanz zu sehen. Dies wird auch durch die steigende Zahl an Studien belegt, die sich speziell mit der Frage nach dem Zusammenhang zwischen Schlafdauer und Übergewicht befassen. Die vorliegende Arbeit gibt einen Überblick sowohl über den aktuellen Stand der Forschung zu diesem Thema als auch über mögliche biologische Mechanismen. Die Evidenz aus epidemiologischen Studien deutet sowohl bei Kindern als auch bei Erwachsenen auf einen Zusammenhang zwischen kurzer Schlafdauer und Übergewicht hin. Die Ergebnisse bei Kindern sind konsistenter als bei Erwachsenen. Als Ursache für den Zusammenhang werden mehrere Mechanismen diskutiert. Dabei stehen vor allem hormonelle Veränderungen im Fokus. Um Schlaf in eine umfassende Strategie zur Bekämpfung von Übergewicht einbeziehen zu können, sind nun Interventionsstudien erforderlich, die einen potenziellen protektiven Effekt einer verlängerten Schlafdauer untersuchen.

Abstract

Sleep deprivation is considered a serious risk factor with a relevant public health impact due to its multiple effects, which we are just beginning to understand. This is underlined by the growing number of studies in recent decades that have investigated the association between sleep duration and overweight. This review gives an overview of the current state of research and potential biological mechanisms. Evidence from epidemiological studies suggests an association between short sleep duration and overweight in children as well as in adults. Different biological mechanisms have been discussed in this context with a special focus on hormonal changes as the potential mediator. To include sleep in a comprehensive strategy to prevent overweight, interventional studies that analyze the potentially protective effect of prolonged sleep duration are necessary.

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Literatur

  1. Harvard Medical School (2010) Benefits of sleep. http://www healthysleep med harvard edu

  2. Hall GS (1904) Adolescence, its psychology and its relations to physiology, anthropology, sociology, sex, crime and education. D. Appleton and Company, New York NY

  3. National Sleep Foundation (2005) Sleep in America poll. http://www.sleepfoundation.org

  4. Kronholm E, Partonen T, Laatikainen T et al (2008) Trends in self-reported sleep duration and insomnia-related symptoms in Finland from 1972–2005: a comparative review and re-analysis of Finnish population samples. J Sleep Res 17:54–62

    Article  PubMed  Google Scholar 

  5. Agras WS, Hammer LD, McNicholas F, Kraemer HC (2004) Risk factors for childhood overweight: a prospective study from birth to 9.5 years. J Pediatr 145:20–25

    Article  PubMed  Google Scholar 

  6. Gillman MW, Rifas-Shiman SL, Kleinman K et al (2008) Developmental origins of childhood overweight: potential public health impact. Obesity (Silver Spring) 16:1651–1656

    Google Scholar 

  7. Kleiser C, Schaffrath RA, Mensink GB et al (2009) Potential determinants of obesity among children and adolescents in Germany: results from the cross-sectional KiGGS Study. BMC Public Health 9:46

    Article  PubMed  Google Scholar 

  8. Nixon GM, Thompson JM, Han DY et al (2008) Short sleep duration in middle childhood: risk factors and consequences. Sleep 31:71–78

    PubMed  Google Scholar 

  9. Ozturk A, Mazicioglu M, Poyrazoglu S et al (2008) The relationship between sleep duration and obesity in Turkish children and adolescents. Acta Paediatr 98:-699

    Google Scholar 

  10. Reilly JJ, Armstrong J, Dorosty AR et al (2005) Early life risk factors for obesity in childhood: cohort study. BMJ 330:1357

    Article  PubMed  Google Scholar 

  11. Dietz WH (1998) Childhood weight affects adult morbidity and mortality. J Nutr 128:411S–414S

    PubMed  CAS  Google Scholar 

  12. SVR – Sachverständigenrat für die Konzertierte Aktion im Gesundheitswesen (2002) Gutachten 2000/2001: Bd. III: Bedarfsgerechtigkeit und Wirtschaftlichkeit. Über-, Unter- und Fehlversorgung. Nomos, Baden-Baden

  13. Nielsen LS, Danielsen KV, Sorensen TI (2011) Short sleep duration as a possible cause of obesity: critical analysis of the epidemiological evidence. Obes Rev 12:78–92

    Article  PubMed  CAS  Google Scholar 

  14. Hense S, Barba G, Pohlabeln H et al (2011) Factors that influence sleep duration in European children. Sleep 34(5):633–639

    PubMed  Google Scholar 

  15. Maurer JT, Schredl M, Weeß HG (2009) Physiologische Grundlagen des normalen und gestörten Schlafes. In: Stuck BA, Maurer JT, Schredl M, Weeß HG (Hrsg) Praxis der Schlafmedizin: Schlafstörungen, schlafbezogene Bewegungs- und Atmungsstörungen, Schnarchen. Diagnostik, Differentialdiagnostik und Therapie. Springer Medizin, Heidelberg

  16. American Academy of Sleep Education (2011) http://www sleepeducation com

  17. Bundeszentrale für Gesundheitliche Aufklärung (BzgA) (2011) Wie viel Schlaf braucht mein Kind? http://www kindergesundheit-info de

  18. Patel SR (2009) Reduced sleep as an obesity risk factor. Obes Rev 10(Suppl 2):61–68

    Article  PubMed  Google Scholar 

  19. Schmid SM, Hallschmid M, Jauch-Chara K et al (2009) Short-term sleep loss decreases physical activity under free-living conditions but does not increase food intake under time-deprived laboratory conditions in healthy men. Am J Clin Nutr 90:1476–1482

    Article  PubMed  CAS  Google Scholar 

  20. Weiss A, Xu F, Storfer-Isser A et al (2010) The association of sleep duration with adolescents‘ fat and carbohydrate consumption. Sleep 33:1201–1209

    PubMed  Google Scholar 

  21. Killgore WD, Kahn-Greene ET, Lipizzi EL et al (2008) Sleep deprivation reduces perceived emotional intelligence and constructive thinking skills. Sleep Med 9:517–526

    Article  PubMed  Google Scholar 

  22. Boyle PJ, Scott JC, Krentz AJ et al (1994) Diminished brain glucose metabolism is a significant determinant for falling rates of systemic glucose utilization during sleep in normal humans. J Clin Invest 93:529–535

    Article  PubMed  CAS  Google Scholar 

  23. Allison DB, Baskin M (2009) Handbook of assessment methods for eating behaviors and weight-related problems: measures, theory, and research, 2. Aufl. SAGE, London, S 224

  24. Wabitsch M, Hebebrand J, Kiess W, Zwiauer KF (2005) Adipositas bei Kindern und Jugendlichen: Grundlagen und Klinik. Springer, Berlin Heidelberg, S 22

  25. Bayer O, Rosario AS, Wabitsch M, Kries R von (2009) Sleep duration and obesity in children: Is the association dependent on age and choice of the outcome parameter? Sleep 32:1183–1189

    PubMed  Google Scholar 

  26. Richelsen B, Pedersen SB, Kristensen K et al (2000) Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients. Metabolism 49:906–911

    Article  PubMed  CAS  Google Scholar 

  27. Mead JR, Irvine SA, Ramji DP (2002) Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med 80:753–769

    Article  PubMed  CAS  Google Scholar 

  28. Spiegel K, Tasali E, Penev P, Van CE (2004) Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 141:846–850

    PubMed  Google Scholar 

  29. Spiegel K, Leproult R, L’hermite-Baleriaux M et al (2004) Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab 89:5762–5771

    Article  PubMed  CAS  Google Scholar 

  30. Chaput JP, Despres JP, Bouchard C, Tremblay A (2007) Short sleep duration is associated with reduced leptin levels and increased adiposity: results from the Quebec family study. Obesity (Silver Spring) 15:253–261

    Google Scholar 

  31. Taheri S, Lin L, Austin D et al (2004) Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 1:e62

    Article  PubMed  Google Scholar 

  32. VanCauter E, Holmback U, Knutson K et al (2007) Impact of sleep and sleep loss on neuroendocrine and metabolic function. Horm Res 67(Suppl 1):2–9

    Article  CAS  Google Scholar 

  33. Ayas NT, White DP, Al-Delaimy WK et al (2003) A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care 26:380–384

    Article  PubMed  Google Scholar 

  34. Gottlieb DJ, Punjabi NM, Newman AB et al (2005) Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch Intern Med 165:863–867

    Article  PubMed  Google Scholar 

  35. Simon C, Weibel L, Brandenberger G (2000) Twenty-four-hour rhythms of plasma glucose and insulin secretion rate in regular night workers. Am J Physiol Endocrinol Metab 278:E413–E420

    PubMed  CAS  Google Scholar 

  36. Boethel CD (2002) Sleep and the endocrine system: new associations to old diseases. Curr Opin Pulm Med 8:502–505

    Article  PubMed  Google Scholar 

  37. Vgontzas AN, Mastorakos G, Bixler EO et al (1999) Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol (Oxf) 51:205–215

    Google Scholar 

  38. Gonzalez-Ortiz M, Martinez-Abundis E, Balcazar-Munoz BR, Pascoe-Gonzalez S (2000) Effect of sleep deprivation on insulin sensitivity and cortisol concentration in healthy subjects. Diabetes Nutr Metab 13:80–83

    PubMed  CAS  Google Scholar 

  39. Nedeltcheva AV, Kessler L, Imperial J, Penev PD (2009) Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. J Clin Endocrinol Metab 94:3242–3250

    Article  PubMed  CAS  Google Scholar 

  40. Spiegel K, Leproult R, Van Cauter E (1999) Impact of sleep debt on metabolic and endocrine function. Lancet 354:1435–1439

    Article  PubMed  CAS  Google Scholar 

  41. Sadeh A (2011) The role and validity of actigraphy in sleep medicine: an update. Sleep Med Rev 15(4):259–267

    Article  PubMed  Google Scholar 

  42. Knutson KL, Spiegel K, Penev P, VanCauter E (2007) The metabolic consequences of sleep deprivation. Sleep Med Rev 11:163–178

    Article  PubMed  Google Scholar 

  43. De Bock F, Fischer JE, Hoffmann K, Renz-Polster H (2010) A participatory parent-focused intervention promoting physical activity in preschools: design of a cluster-randomized trial. BMC Public Health 10:49

    Article  Google Scholar 

  44. Bell JF, Zimmerman FJ (2010) Shortened nighttime sleep duration in early life and subsequent childhood obesity. Arch Pediatr Adolesc Med 164:840–845

    Article  PubMed  Google Scholar 

  45. Calamaro CJ, Park S, Mason TB et al (2010) Shortened sleep duration does not predict obesity in adolescents. J Sleep Res 19:559–566

    Article  PubMed  Google Scholar 

  46. Hairston KG, Bryer-Ash M, Norris JM et al (2010) Sleep duration and five-year abdominal fat accumulation in a minority cohort: the IRAS family study. Sleep 33:289–295

    PubMed  Google Scholar 

  47. Lauderdale DS, Knutson KL, Rathouz PJ et al (2009) Cross-sectional and longitudinal associations between objectively measured sleep duration and body mass index: the CARDIA Sleep Study. Am J Epidemiol 170:805–813

    Article  PubMed  Google Scholar 

  48. Nishiura C, Noguchi J, Hashimoto H (2010) Dietary patterns only partially explain the effect of short sleep duration on the incidence of obesity. Sleep 33:753–757

    PubMed  Google Scholar 

  49. Seegers V, Petit D, Falissard B et al (2011) Short sleep duration and body mass index: a prospective longitudinal study in preadolescence. Am J Epidemiol 173:621–629

    Article  PubMed  Google Scholar 

  50. Watanabe M, Kikuchi H, Tanaka K, Takahashi M (2010) Association of short sleep duration with weight gain and obesity at 1-year follow-up: a large-scale prospective study. Sleep 33:161–167

    PubMed  Google Scholar 

  51. Chaput JP, Despres JP, Bouchard C, Tremblay A (2008) The association between sleep duration and weight gain in adults: a 6-year prospective study from the Quebec Family Study. Sleep 31:517–523

    PubMed  Google Scholar 

  52. Gangwisch JE, Malaspina D, Boden-Albala B, Heymsfield SB (2005) Inadequate sleep as a risk factor for obesity: analyses of the NHANES I. Sleep 28:1289–1296

    PubMed  Google Scholar 

  53. Hasler G, Buysse DJ, Klaghofer R et al (2004) The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep 27:661–666

    PubMed  Google Scholar 

  54. Littman AJ, Vitiello MV, Foster-Schubert K et al (2007) Sleep, ghrelin, leptin and changes in body weight during a 1-year moderate-intensity physical activity intervention. Int J Obes (Lond) 31:466–475

    Google Scholar 

  55. Lopez-Garcia E, Faubel R, Leon-Munoz L et al (2008) Sleep duration, general and abdominal obesity, and weight change among the older adult population of Spain. Am J Clin Nutr 87:310–316

    PubMed  CAS  Google Scholar 

  56. Patel SR, Malhotra A, White DP et al (2006) Association between reduced sleep and weight gain in women. Am J Epidemiol 164:947–954

    Article  PubMed  Google Scholar 

  57. Stranges S, Cappuccio FP, Kandala NB et al (2008) Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II Study. Am J Epidemiol 167:321–329

    Article  PubMed  Google Scholar 

  58. Cappuccio FP, Taggart FM, Kandala NB et al (2008) Meta-analysis of short sleep duration and obesity in children and adults. Sleep 31:619–626

    PubMed  Google Scholar 

  59. Patel SR, Blackwell T, Redline S et al (2008) The association between sleep duration and obesity in older adults. Int J Obes (Lond) 32:1825–1834

    Google Scholar 

  60. Landhuis CE, Poulton R, Welch D, Hancox RJ (2008) Childhood sleep time and long-term risk for obesity: a 32-year prospective birth cohort study. Pediatrics 122:955–960

    Article  PubMed  Google Scholar 

  61. Lumeng JC, Somashekar D, Appugliese D et al (2007) Shorter sleep duration is associated with increased risk for being overweight at ages 9–12 years. Pediatrics 120:1020–1029

    Article  PubMed  Google Scholar 

  62. Snell EK, Adam EK, Duncan GJ (2007) Sleep and the body mass index and overweight status of children and adolescents. Child Dev 78:309–323

    Article  PubMed  Google Scholar 

  63. Taveras EM (2008) Short sleep duration in infancy and risk of childhood overweight. Arch Pediatr Adolesc Med 162:305–311

    Article  PubMed  Google Scholar 

  64. Touchette E, Mongrain V, Petit D et al (2008) Development of sleep-wake schedules during childhood and relationship with sleep duration. Arch Pediatr Adolesc Med 162:343–349

    Article  PubMed  Google Scholar 

  65. Börnhorst C, Hense S, Ahrens W et al (2011) From sleep duration to childhood obesity – what are the key pathways? (im Review)

  66. Gustafson P (2004) Measurement error and misclassification in statistics and epidemiology. Chapman & Hall/CRC, Boca Raton, S 9–30

  67. Marshall NS, Glozier N, Grunstein RR (2008) Is sleep duration related to obesity? A critical review of the epidemiological evidence. Sleep Med Rev 12:289–298

    Article  PubMed  Google Scholar 

  68. Cizza G, Marincola P, Mattingly M et al (2010) Treatment of obesity with extension of sleep duration: a randomized, prospective, controlled trial. Clin Trials 7:274–285

    Article  PubMed  Google Scholar 

  69. Philipsen NM, Philipsen NC (2008) Childhood overweight: prevention strategies for parents. J Perinat Educ 17:44–47

    Article  PubMed  Google Scholar 

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Danksagung

Unser besonderer Dank gilt Frau Prof. Iris Pigeot (BIPS) für die Unterstützung beim Erstellen des Manuskriptes.

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Authors and Affiliations

  1. Bremer Institut für Präventionsforschung und Sozialmedizin (BIPS), Universität Bremen, Achterstr. 30, 28359, Bremen, Deutschland

    S. Hense

  2. Institut für Soziale Pädiatrie und Jugendmedizin, LMU München, München, Deutschland

    O. Bayer

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  1. S. Hense
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  2. O. Bayer
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Correspondence to S. Hense.

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Hense, S., Bayer, O. Schlafdauer und Übergewicht. Bundesgesundheitsbl. 54, 1337–1343 (2011). https://doi.org/10.1007/s00103-011-1368-0

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